Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals.
For non-prescription products, read the label or package ingredients carefully. No information is available on the relationship of age to the effects of methylprednisolone in the pediatric population. Safety and efficacy have not been established.
No information is available on the relationship of age to the effects of methylprednisolone in geriatric patients. There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding. Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur.
In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below.
The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive. Using this medicine with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take. Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases.
If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines. Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur.
Using alcohol or tobacco with certain medicines may also cause interactions to occur. The presence of other medical problems may affect the use of this medicine.
Make sure you tell your doctor if you have any other medical problems, especially:. Take this medicine exactly as directed by your doctor. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered.
However, because drugs affect each person differently, we cannot guarantee that this information includes all possible side effects. This information is not a substitute for medical advice. Always discuss possible side effects with a healthcare provider who knows your medical history. Methylprednisolone oral tablet can interact with other medications, vitamins , or herbs you may be taking.
An interaction is when a substance changes the way a drug works. This can be harmful or prevent the drug from working well. To help avoid interactions, your doctor should manage all of your medications carefully. Do not take these drugs with methylprednisolone.
When used with methylprednisolone, these drugs can cause dangerous effects in the body. Examples of these drugs include:. Taking methylprednisolone with certain medications raises your risk of side effects from methylprednisolone. This is because the amount of methylprednisolone in your body is increased. Taking methylprednisolone with certain medications raises your risk of side effects from these drugs. When methylprednisolone is used with certain drugs, it may not work as well to treat your condition.
This is because the amount of methylprednisolone in your body may be decreased. However, because drugs interact differently in each person, we cannot guarantee that this information includes all possible interactions.
Always speak with your healthcare provider about possible interactions with all prescription drugs, vitamins, herbs and supplements, and over-the-counter drugs that you are taking.
This dosage information is for methylprednisolone oral tablet. All possible dosages and forms may not be included here. Your dosage, form, and how often you take it will depend on:. They should give your child the lowest effective dosage. The kidneys of older adults may not work as well as they used to. This can cause your body to process drugs more slowly.
As a result, more of a drug stays in your body for a longer time. This raises your risk of side effects. Your doctor may start you on a lowered dose or a different dosing schedule.
This can help keep levels of this drug from building up too much in your body. However, because drugs affect each person differently, we cannot guarantee that this list includes all possible dosages. Always speak with your doctor or pharmacist about dosages that are right for you. This drug may cause hormone changes. It can cause your body to stop making hormones on its own. If you respond well to your dosage of this drug, your doctor may slowly reduce your dosage to reduce your risk of side effects.
This drug can weaken your immune system. This makes it easier for you to get infections and harder for you to fight infections. While you take this drug, you should stay away from people who are sick or who have recently been sick. This includes people who have chickenpox, measles, or the flu. Sign up for prednisone price alerts and find out when the price changes! Get price alerts. Methylprednisolone is used in the treatment of a wide variety of disease states and disorders.
Its effect on the inflammatory process makes it useful in rheumatic disorders such as rheumatoid and psoriatic arthritis, spondylitis, and bursitis. It is also used to treat acute flares of bronchial asthma. The immunosuppressive properties of methylprednisolone make it an effective treatment in allergic conditions such as acute allergic rhinitis, contact dermatitis, and drug sensitivity reactions.
It is also used in endocrine, collagen, hematologic, gastrointestinal, and ophthalmic disorders. Prednisone is also used to treat a wide range of inflammatory and autoimmune disorders similar to methylprednisolone. These include rheumatic, respiratory, allergic, endocrine, collagen, hematologic, gastrointestinal, and ophthalmic disorders.
The following table, while extensive, may not list every use of these two medications. Please consult with your healthcare provider for more information on indications of use. There are many ways to compare methylprednisolone and prednisone due to their wide range of uses. In most inflammatory processes, treatment with corticosteroids is limited to short term use in severe and acute exacerbations of the disorder.
When comparing methylprednisolone and prednisone directly, 4 mg of methylprednisolone is the equivalent of 5 mg of prednisone. However, when doses are adjusted and monitored for response, each can be effective in treatment. One study sought to compare the effects of intravenous methylprednisolone to oral prednisone in acute asthma exacerbations in children. Two treatment groups were randomized to receive either 30 mg of intravenous methylprednisolone or 30 mg of oral prednisone.
Both groups received albuterol, and researchers evaluated symptomatic relief, peak expiratory flow PEF , and pulse oximetry readings.
Readings were taken for each group at two, four, and six hours after beginning treatment. There was no clinically or statistically significant difference at each interval between the two groups.
Researchers concluded that oral prednisone would be the superior choice due to lower cost and a less traumatic administration. Sign up for methylprednisolone price alerts and find out when the price changes! Methylprednisolone is a prescription medication that is typically covered by both commercial insurance plans as well as Medicare.
Prednisone is also a prescription medication typically covered by both commercial insurance plans and Medicare. It is important to note that for certain disease states, corticosteroids may not be covered under the medicare drug benefit, but may be covered under Medicare Part B.
Your pharmacist can provide more information on coverage. Prednisone is metabolized to its active metabolite prednisolone by the liver. Prednisolone and methylprednisolone are chemically very similar, and therefore their potential side effects closely mirror each other.
Glucocorticoids are known to cause fluid and electrolyte imbalances which may lead to sodium and fluid retention, high blood pressure, and in some cases, congestive heart failure.
Call your doctor if you have any signs of infection fever, chills, body aches. If you have major surgery or a severe injury or infection, your methylprednisolone dose needs may change. Make sure any doctor caring for you knows you are using this medicine. Call your doctor for instructions if you miss an appointment for your methylprednisolone injection.
Methylprednisolone works quickly. It reaches its peak effect within about one hour after an intravenous dose. Its peak effect is about two hours when given orally.
Let your provider know if you experience any unusual side effects after receiving this medicine. Methylprednisolone is prescribed for many different health problems. Health Topics. Health Tools. Methylprednisolone Medrol. Reviewed: January 18, Tell your doctor if you have ever had: heart disease, high blood pressure; a thyroid disorder; diabetes; glaucoma or cataracts; kidney disease; cirrhosis or other liver disease; seizures, epilepsy or recent head injury; past or present tuberculosis; herpes infection of the eyes; a condition called scleroderma; stomach ulcers, ulcerative colitis, diverticulitis, or recent intestinal surgery; a parasite infection that causes diarrhea such as threadworms ; mental illness or psychosis; osteoporosis or low bone mineral density steroid medication can increase your risk of bone loss ; a muscle disorder such as myasthenia gravis; or an electrolyte imbalance such as low levels of potassium in your blood.
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